Since 2019, COVID-19 erupted in many countries. The epidemic prevention measures of many cities caused their factories to stop production. Digitalization of business operations was suddenly on the verge, with smart factories becoming the focus of investment in the manufacturing industry. Coupled with the international commitment for carbon reduction worldwide and Environmental, Social and Corporate Governance (ESG) demand for sustainable operation, corporations are vying to expand their capital in smart manufacturing. The global smart manufacturing market reached USD$305 billion in 2021, and is expected to reach USD$450 billion by 2025. Taiwan's Electronic Manufacturing Services (EMS) for laptop computers, mobile phones & consumer electronics has no rival in terms of manufacturing technology, cost control, and supply chain management. After decades of research, it has integrated many smart factory solutions. Among the latest batch of 21 new manufacturing sites to join the Global Lighthouse Network announced by the World Economic Forum 2021, Taiwan's Innolux Kaohsiung factory, AUO Taichung factory (Fab3), and Foxconn Zhengzhou and Wuhan factories were selected. Taiwan’s world-famous chip manufacturer TSMC has moved further towards 3nm and smaller sizes, taking a revolutionary approach to create a smart integrated factory. It’s expected to be more effective and comprehensive in improving productivity, flexibility, efficiency and product quality. There are more companies in Taiwan that have already used smart factories to upgrade their value and regard smart factories as the key to staying ahead of the competition. In the future, it’s expected that the manufacturing industry will frequent more challenges stemming from manufacturing instability due to climate change, infectious diseases, and labor shortages. It is our goal and desire that through this book we may help the international community take stock of Taiwan’s smart manufacturing solution providers and that we embark together in the transformation and upgrade of manufacturing industries.